Prophylaxis with Artemisia annua is Very Efficient: The Role of Chelators

Submit Manuscript | http://medcraveonline.com could be evidenced for these drugs. Willcox is right in stating that no large scale, randomized, double blind clinical trials confirming the efficiency of Artemisia plants against malaria are available. Indeed, they are forbidden by WHO. Only clinical trials with ACTs have been run in high numbers. OXFAM and others even claim that Africans are guinea pigs for pills or vaccines from Bigpharma WHO. Fortunately, some African medical doctors have decided not to obey the ludicrous veto of WHO Geneva and obtained the authorization of their health authorities to run clinical trials, small or large scale, with Artemisia annua or Artemisia afra: in Cameroon, in Mali, in Kenya, in RDCongo, in Senegal, in The Gambia, in Benin, in Ethiopia, in Tanzania, in Uganda, in Mozambique. They all assess a cure rate of >95 % for uncomplicated malaria, much higher than for ACTs. This all was confirmed by a large-scale trial in the province of Maniema, RDCongo of Artemisia annua and Artemisia afra vs ASAQ: 1000 patients, randomized, double blind. The herbal treatment was in all aspects superior: for fever clearance, parasitemia clearance, gametocytemia clearance, with no adverse effects and a virtual absence of recurrence on day 28. The trial included 465 children from 2-5 years of age. But these were all symptomatic patients and the question of the efficacy of Artemisia tea infusions on asymptomatic carriers remained open. Dr. Jerome Munyangi has now completed a first randomized trial with 2x100 primary school children in the province of Maniema. The objective was to study the impact of a prophylactic treatment of 3 cups/week Artemisia annua infusion. The results are overwhelming. In the second and third month of the treatment parasitemia and gametocytemia have completely disappeared in the Artemisia arm, but in the control arm the parasite carriage remains constant over the 3 months The seminal discovery in this small trial, which will be repeated in more schools, is of course that the prophylactic effect is evident, but more important: that the treated children will not transmit gametocytes to mosquitoes biting them. Based on these results it may be concluded that only Artemia tea infusion or powdered leaves have a lasting gametocytocidal effect. ACT’s do not, and dihydroartemisininpiperaquine may even prolong the gametocyte carriage [1].